BDBM50269849 CHEMBL4076748

SMILES CC(=O)N1CCc2c(C1)c(nn2C1CCOCC1)N1CCCc2cc(-c3cnn(C)c3)c(cc12)C(F)F

InChI Key InChIKey=LWXLECMNBTVASW-UHFFFAOYSA-N

Data  15 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50269849   

TargetBromodomain-containing protein 8(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50269849(CHEMBL4076748)
Affinity DataIC50: >2.00E+4nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from recombinant His-tagged BRD8 bromodomain-1 (unknown origin) measured after 10 mins by T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed